Induction of ΔFosB in the Periaqueductal Gray by Stress Promotes Active Coping Responses
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چکیده
منابع مشابه
Induction of ΔFosB in the Periaqueductal Gray by Stress Promotes Active Coping Responses
We analyzed the influence of the transcription factor DeltaFosB on learned helplessness, an animal model of affective disorder wherein a subset of mice exposed to inescapable stress (IS) develop a deficit in escape behavior. Repeated IS induces DeltaFosB in the ventrolateral periaqueductal gray (vlPAG), and levels of the protein are highly predictive of an individual's subsequent behavorial def...
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ژورنال
عنوان ژورنال: Neuron
سال: 2007
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2007.10.028